A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/00 (2006.01) A61K 31/427 (2006.01) A61K 38/00 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/66 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2539281
The MINOR and TR3 genes are disclosed to be insulin responsive genes differentially expressed as a function of insulin resistance and Type 2 Diabetes in humans and a variety of well characterized animal models. The present disclosure shows that MINOR and TR3 have a functional role in insulin resistance. Therefore, MINOR and TR3 are attractive and novel therapeutic targets for combating insulin resistance and/or disease states and conditions characterized by insulin resistance. Correlation of insulin resistance and disease states and conditions characterized by insulin resistance, including Type II diabetes, with MINOR and TR3 gene expression are also disclosed. Methods of diagnosis, treatment and prevention are likewise disclosed for the treatment and/or prevention of insulin resistance and disease states or conditions characterized by insulin resistance. The use an activated insulin responsive gene selected from the group consisting of MINOR, TR3 and MINOR and TR3 for treating or preventing insulin resistance in a subject is also disclosed.
Fu Yuchang
Garvey W. Timothy
Martin Mitchell Lee
F. Hoffman-La Roche Ag
Fogler Rubinoff Llp
The Uab Research Foundation
LandOfFree
Methods for the treatment of insulin resistance and disease... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for the treatment of insulin resistance and disease..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for the treatment of insulin resistance and disease... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1494224