Methods for the treatment of osteoporosis

Details Methods for the treatment of osteoporosis Methods for the treatment of osteoporosis

A - Human Necessities

61

K

A61K 31/66 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2101275

Methods of treatment for osteoporosis in a human or other animal subject, comprising: administering a bone-active phosphonate to said subject, at a level of at least about 0.1 LED per day of said treatment; and administering an estrogen hormone to said subject at a level of from about 0.2 to about 0.8 LED per day of said treatment. The bone-active phosphonate is preferably a bisphosphonate, or a phosphonoalkyl phosphonate.

Méthode de traitement de l'ostéoporose chez un sujet humain ou animal. La méthode consiste à administrer au sujet un phosphonate qui agit sur les os (plus faible dose efficace d'au moins 0,1 par jour), ainsi qu'un oestrogène (plus faible dose efficace d'au moins 0,2 à 0,8 par jour). Le phosphonate actif pour les os est de préférence un bisphosphonate ou un phosphonate phosphonoalkyl.

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