Methods for the treatment of pain comprising opioid antagonists

Details Methods for the treatment of pain comprising opioid antagonists Methods for the treatment of pain comprising opioid antagonists

A - Human Necessities

61

K

A61K 31/485 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2522471

Methods and compositions for treating subjects with pain, including neuropathic pain, using the antagonists naloxon, naltrexon or nalmefene or combinations of these antagonists and opioid agonists, wherein the amount of an opioid antagonist enhances the neuropathic pain-alleviating potency of an opioid agonist.

L'invention concerne des procédés et des compositions permettant de traiter des patients souffrant de douleurs, y compris des douleurs neuropathiques, par des antagonistes opioïdes ou des combinaisons d'antagonistes opioïdes et d'agonistes opioïdes, notamment lorsque la dose d'un antagoniste opioïde renforce la puissance d'atténuation de douleurs neuropathiques d'un agoniste opioïde.

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