Methods for treating a physiological disorder associated...

Details Methods for treating a physiological disorder associated... Methods for treating a physiological disorder associated...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 31/00 (2006.01) A61K 31/335 (2006.01) A61K 31/365 (2006.01)

Patent

CA 2152765

This invention describes methods for treating conditions associated with an .beta.-amyloid peptide, such as Alzheimer's disease or Down's Syndrome, in a mammal which comprises administering to the mammal in need thereof an effective amount of a derivative of a vacuolar adenotriphosphatase inhibitor or a pharmaceutically acceptable salt or prodrug thereof. This invention also describes methods for treating conditions associated with .beta.-amyloid-associated toxicity in a mammal which comprises administering to the mammal an effective amount of a bafilomycin or concanamycin antibiotic or a pharmaceutically acceptable salt or prodrug thereof.

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