Methods for treating acute myocardial infarctions and...

A - Human Necessities – 61 – K

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A61K 31/4418 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2747251

The invention relates to methods of treating patients who have suffered an acute myocardial infarction (AMI) with a therapeutic that has anti-fibrotic effects, for example, pirfenidone and analogs thereof The method of treating a patient who has suffered an acute myocardial infarction may include administering to the patient a therapeutically effective dose of a therapeutic having an anti-fibrotic effect, wherein optionally the treatment is initiated at a time period about 1 to 42 days after suffering the AMI, and optionally continues for up to 3 to 6 months

L'invention concerne des méthodes de traitement de patients qui ont souffert d'un infarctus du myocarde aigu (AMI) avec un agent thérapeutique qui possède des effets anti-fibreux, par exemple, la pirfénidone et ses analogues. La méthode de traitement d'un patient qui a souffert d'un infarctus du myocarde aigu peut comprendre l'administration au patient d'une dose efficace d'un point de vue thérapeutique d'un agent thérapeutique possédant un effet anti-fibreux, le traitement étant facultativement commencé environ 1 à 42 jours après l'occurrence de l'AMI, et continuant facultativement pendant 3 à 6 mois.

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