A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/39 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2482042
The present invention relates to compositions and methods for treating immune system diseases such as rheumatic disease, by administering to a subject soluble CTLA4 molecules that block endogenous B7 molecules from binding their ligands, alone, or in conjunction with other agents including Disease Modifying Anti-Rheumatic Drugs (DMARDs).
La présente invention concerne des compositions et des méthodes permettant de traiter des maladies du système immunitaire, telles que du rhumatisme, par administration, à un sujet, de molécules CTLA4 solubles empêchant les molécules endogènes B7 molécules de se lier à leurs ligands, seules ou conjointement avec d'autres agents parmi lesquels, les antirhumatismaux modificateurs de la maladie (ARMM).
Becker Jean-Claude
Carr Suzette
Cohen Robert
Hagerty David
Peach Robert J.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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