Methods for treating aneurysms

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/74 (2006.01) A61B 17/12 (2006.01) A61F 2/06 (2006.01) A61K 31/722 (2006.01) A61K 31/765 (2006.01) A61K 31/785 (2006.01) A61K 47/30 (2006.01) A61K 47/38 (2006.01) A61B 17/00 (2006.01) A61F 2/00 (2006.01) A61M 25/10 (2006.01)

Patent

CA 2409104

This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.

L'invention concerne des méthodes de traitement d'anévrismes, le sac anévrismal étant rempli d'un ou de plusieurs agents non particulaires et/ou d'une composition fluidique se solidifiant in situ. Le remplissage du sac anévrismal met en oeuvre une quantité suffisante d'un ou de plusieurs agents non particulaires et/ou de la composition fluidique en vue d'inhiber le flux sanguin dans le sac anévrismal. De plus, les méthodes selon l'invention permettent une isolation non endogène de l'artère principale proximale et distale par rapport au sac anévrismal du flux sanguin systémique du mammifère traité. La combinaison de ces caractéristiques permet un traitement du sac anévrismal, tout en inhibant la formation d'anévrisme et/ou de nouvelle croissance dans les parties malades de la paroi artérielle proximale et distale par rapport à l'anévrisme traité.

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