Methods for treating arthritic conditions in dogs

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/445 (2006.01) A61K 31/19 (2006.01)

Patent

CA 2565079

The present invention relates to a method for eliciting a disease modifying effect on an arthritic condition in a hip or stifle of a canine which comprises administering to the canine a therapeutically effective amount of a bisphosphonate. The present invention also relates to method for eliciting a disease modifying effect on hip dysplasia or stifle instability, the pain associated with hip dysplasia or stifle instability, joint swelling, shallowing of the acetabulum, narrowing of the joint space, subchondral bone sclerosis, preventing osteophyte formation and preventing joint destruction in a canine which comprises administering to the canine a therapeutically effective amount of a bisphosphonate.

La présente invention concerne une méthode pour provoquer un effet de modification de la maladie sur un état arthritique au niveau d'une hanche ou d'un grasset d'un animal canin. Ladite méthode consiste à administrer à l'animal canin une quantité thérapeutiquement efficace d'un bisphosphonate. La présente invention concerne également une méthode pour provoquer un effet de modification de la maladie sur une dysplasie de la hanche ou une instabilité du grasset, pour traiter une douleur associée à la dysplasie de la hanche ou à l'instabilité du grasset, un oedème articulaire, un creusement de l'acétabulum, un rétrécissement de l'espace articulaire, une ostéosclérose sous-chondrale, pour empêcher la formation d'ostéophytes et pour empêcher la destruction articulaire chez un animal canin. Ladite méthode consiste à administrer à l'animal canin une quantité thérapeutiquement efficace d'un bisphosphonate.

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