A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/00 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2651791
In various embodiments, the present invention provides methods and compositions for treatment of autoimmune diseases, including rheumatoid arthritis, for example comprising administering to a patient in need of such treatment a TACI-Ig fusion molecule. In one embodiment, the TACI-Ig fusion molecule is administered in amount sufficient to slow, suppress or inhibit proliferation-inducing functions of BIyS and APRIL.
Dans divers modes de réalisation, la présente invention propose des procédés et des compositions permettant le traitement des maladies auto-immunes, dont la polyarthrite rhumatoïde par exemple, comprenant l'administration à un patient ayant besoin d'un tel traitement d'une molécule de fusion TACI-Ig. Dans un mode de réalisation, la molécule de fusion TACI-Ig est administrée en quantité suffisante pour ralentir, supprimer ou inhiber les fonctions d'induction de prolifération de BiyS et APRIL.
Broly Herve
Busby Sharon
Gross Jane
Nestorov Ivan
Visich Jennifer
Ares-Trading S.a.
Borden Ladner Gervais Llp
Zymogenetics Inc.
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