Methods for treating autoimmune disorders

Details Methods for treating autoimmune disorders Methods for treating autoimmune disorders

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 38/20 (2006.01)

Patent

CA 2591587

The present invention relates to methods for treating autoimmune disorders. In an embodiment, the invention is directed to a method for treating an autoimmune disorder comprising administering a TCCR agonist. In an embodiment, the autoimmune disorder is at least partially mediated by a Th1 response. In an embodiment, the autoimmune disorder is at least partially mediated by CD8+T- cell proliferation.

L'invention concerne des procédés permettant de traiter des troubles auto-immuns. Dans un mode de réalisation, l'invention concerne un procédé permettant de traiter un trouble auto-immun, qui consiste en l'administration d'un agoniste TCCR. Dans un autre mode de réalisation, le trouble auto-immun est au moins partiellement médié par une réponse de Th1. Dans un autre mode de réalisation encore, le trouble auto-immun est au moins partiellement médié par la prolifération de lymphocytes T CD8+.

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