Methods for treating b-cell malignancies using taci-ig...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2618765

The present invention provides methods and compositions for treatment of B- cell malignancies, including non-Hodgkin's lymphoma, comprising administering to a patient in need of the treatment a TACI-Ig fusion molecule in amount sufficient to suppress proliferation-inducing functions of BIyS and APRIL.

L'invention concerne des procédés et des compositions destinés au traitement des malignités des lymphocytes B, notamment les lymphomes non-Hodgkiniens, qui consistent à administrer à un patient le nécessitant le traitement d'une molécule de fusion TACI-Ig en quantité suffisante à supprimer les fonctions induisant la prolifération de BIyS et d'APRIL.

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