Methods for treating cancer by inhibiting wnt signaling

Details Methods for treating cancer by inhibiting wnt signaling Methods for treating cancer by inhibiting wnt signaling

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61K 51/00 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12Q 1/00 (2006.01) C12Q 1/18 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2501235

This invention relates to methods of inhibiting the growth of cancer cells that overexpress a Wnt protein. The methods comprise contacting the cell with an agent that inhibits binding of the Wnt protein to a Frizzled receptor.

L'invention se rapporte à des méthodes d'inhibition de la croissance de cellules cancéreuses qui surexpriment une protéine Wnt. Ces procédés consistent à mettre en contact ladite cellule avec un agent qui inhibe la liaison de la protéine Wnt avec le récepteur Frizzled.

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