Methods for treating cancer with mva

Details Methods for treating cancer with mva Methods for treating cancer with mva

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 31/337 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/07 (2006.01) C07K 14/71 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2665068

The invention relates to compositions, kits, and methods for cancer therapy using recombinant MVA viruses encoding a tumor-associated antigen, such as HER-2, particularly in combination with taxanes. The taxanes can be administered prior to, at the same time as, or after the recombinant MVA virus.

La présente invention concerne des compositions, des trousses et des méthodes de thérapie anticancer dans lesquelles on utilise des virus MVA de recombinaison codant un antigène associé aux tumeurs, tel que HER-2, notamment en combinaison avec des taxanes. Les taxanes peuvent être administrés avant le virus MVA de recombinaison, en même temps que ce dernier ou bien encore après ledit virus MVA de recombinaison.

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