A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 11/00 (2006.01) C07K 16/24 (2006.01)
Patent
CA 2475529
The present disclosure relates to the use of an antibody against interleukin-8 in the preparation of a medicament for treating Chronic Obstructive Pulmonary Disease (COPD) or any one of its indications, including for example, chronic bronchitis, emphysema, and irreversible asthma. The disclosure also provides methods of treating Chronic Obstructive Pulmonary Disease (COPD) and its various indications, particularly including chronic bronchitis, emphysema, and irreversible asthma. Treatment regimens generally include the administration of anti-interleukin-8 antibodies to the patient to reduce the severity of an inflammatory response by the patient's immune system.
La présente invention concerne l'utilisation d'un anticorps dirigé contre l'interleukine 8 dans la préparation d'un médicament destiné à traiter une broncho-pneumopathie chronique obstructive (BPCO) ou une autre maladie pour laquelle cet anticorps est indiqué, comprenant par exemple, la bronchite chronique, l'emphysème et l'asthme irréversible. Cette invention concerne aussi des techniques de traitement de la broncho-pneumopathie chronique obstructive (BPCO) ou d'une des diverses maladies pour lesquelles cet anticorps est indiqué, notamment en particulier, la bronchite chronique, l'emphysème et l'asthme irréversible. Des traitements consistent en général à administrer des anticorps anti-interleukine 8 au patient de façon à réduire la gravité d'une réponse inflammatoire du système immunitaire du patient.
Bell Gregory M.
Gladue Ronald P.
Kudlacz Elizabeth M.
Showell Henry J.
Yang Xiao-Dong
Abgenix Inc.
Pfizer Inc.
Smart & Biggar
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