Methods for treating immune disorders associated with graft...

A - Human Necessities – 61 – K

Patent

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A61K 38/17 (2006.01)

Patent

CA 2603970

The present invention provides use of soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and/or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig in the treatment of immune disorders associated with graft transplantation.

L'invention porte sur des molécules solubles de CTLA4 mutant qui se fixent avec une plus grande affinité aux antigènes CD80 et/ou CD86 que les CTLA4 de type sauvage ou que les CTLA4Ig mon mutants, pour le traitement de troubles immunologiques associés à des transplantations de greffes.

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