A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/573 (2006.01) A61K 9/00 (2006.01) A61K 47/34 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61K 9/56 (2006.01)
Patent
CA 2414680
Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 µg/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 µg/ml dexamethasone for at least about three weeks.
L'invention concerne des procédés servant à traiter des états inflammatoires de l'oeil et consistant à implanter dans le corps vitré un implant bioérodable composé d'un agent stéroïde anti-inflammatoire et d'un polymère bioérodable, cet implant diffusant cet agent dans le corps vitré en quantités suffisantes pour atteindre une concentration équivalente à au moins 0,05 microgramme/millilitre de déxaméthasone en 48 heures et maintient une concentration équivalente à 0,03 microgramme/millilitre de déxaméthasone pendant au moins trois semaines.
Hu Mae W. L.
Wong Vernon G.
Allergan Inc.
Borden Ladner Gervais Llp
Oculex Pharmaceuticals Inc.
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