Methods for treating kidney disorders

Details Methods for treating kidney disorders Methods for treating kidney disorders

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2647268

Provided are methods of treating kidney disorders in a subject by administering an effective amount of VEGFR agonist, e.g., a Flt1 agonist to a subject. The agonists are composed of compositions comprising VEGFR agonists, e.g., VEGF, antibodies directed to Flt1, Flt1 ligands, Flt1 small molecule activators, or Flt1 selective agents in a pharmaceutically acceptable carrier for use in activating Flt1.

L'invention concerne des méthodes pour traiter des troubles rénaux chez un sujet en administrant à un sujet une quantité efficace d'agoniste VEGFR, par exemple, un agoniste Flt1. Les agonistes contiennent des compositions qui comprennent des agonistes VEGFR, par exemple, VEGF, des anticorps dirigés contre Flt1, des ligands Flt1, des activateurs Flt1 de petites molécules ou des agents sélectifs Flt1 dans un véhicule pharmaceutiquement acceptable à utiliser pour activer Flt1.

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