C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2528120
The present invention provides methods of identifying an agent that inhibits an activity of a lentiviral Vif protein. The present invention provides methods of identifying an agent that increases the level of active APOBEC3G in a cell. The present invention provides agents identified by a subject screening method; and further provides methods for treating lentivirus infections.
L'invention concerne des procédés d'identification d'un agent qui inhibe une activité de protéine Vif lentivirale. Cette invention concerne des procédés d'identification d'un agent qui augmente le niveau d'APOBEC3G actif dans une cellule. Elle concerne également des agents identifiés par un procédé de criblage de sujet; et des procédés de traitement d'infections par le lentivirus.
Chiu Ya-Lin
de Noronha Carlos Manuel Clemm
Greene Warner C.
Soros Vanessa B.
Stopak Kimberly Sue
Fetherstonhaugh & Co.
The J. David Gladstone Institutes
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