A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2569406
The present invention provides methods of inhibiting mast cell activity by administering a selective inhibitor of phosphoinositide 3-kinase delta (P13K.delta.). The invention also provides methods for treating or preventing a condition associated with undesirable mast cell activity in an individual comprising administering an effective amount of a selective P13K.delta. inhibitor.
La présente invention concerne des méthodes destinées à inhiber l'activité des mastocytes par administration d'un inhibiteur sélectif de la phosphoinositide 3-kinase delta (P13K?). Elle concerne également des méthodes de traitement ou de prévention d'un état associé à une activité indésirable des mastocytes chez un individu, qui consistent à administer audit individu une quantité efficace d'un inhibiteur sélectif de P13K?.
Hayflick Joel S.
Kawakami Toshi
Kawakami Yuko
Pefaur Noah
Puri Kamal D.
Icos Corporation
La Jolla Institute For Allergy And Immunology
Ridout & Maybee Llp
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