Methods for treating neoplasia with combination of...

Details Methods for treating neoplasia with combination of... Methods for treating neoplasia with combination of...

A - Human Necessities

61

K

A61K 31/7076 (2006.01) A61K 41/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2683637

Methods for treating neoplasia with a chemotherapeutic agent and radiation are provided. Radiation therapies used in conjuction with a compound described herein presents a synergistic effect in the treatment of cancers. A compound of formula (I): wherein X, Y, Z, R1 and R2 are defined herein, sensitize cells making them more susceptible to radiation therapy.

L'invention concerne des méthodes de traitement de la néoplasie avec un agent chimiothérapeutique et un rayonnement. Les radiothérapies utilisées conjointement à un composé décrit ici présentent un effet synergique dans le traitement de cancers. Un composé de formule (I) : où X, Y, Z, R1 et R2 sont définis ici, sensibilise les cellules les rendant plus réceptives à une radiothérapie.

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