Methods for treating or preventing sclerotic disorders using...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) A61K 35/26 (2006.01) A61K 35/28 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2454618

Methods and compositions for treating or preventing fibrotic disorders, e.g., sclerotic disorders, for example scleroderma, using CD2-binding agents, e.g., LFA-3/IgG fusion polypeptides or LFA-3-binding agents, are provided.

L'invention concerne des méthodes et des compositions destinées au traitement ou à la prévention de troubles fibrogènes, notamment de troubles scléreux, par exemple, la dermatosclérose, par utilisation d'agents se liant à CD2, de polypeptides de fusion LFA-3/IgG ou d'agents se liant à LFA-3.

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