Methods for treating osteoarthritis using an estrogen...

Details Methods for treating osteoarthritis using an estrogen... Methods for treating osteoarthritis using an estrogen...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/138 (2006.01) A61K 31/341 (2006.01) A61K 31/365 (2006.01) A61K 31/4025 (2006.01) A61K 31/404 (2006.01) A61K 31/415 (2006.01) A61K 31/439 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/453 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) A61K 31/55 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2357467

The present invention provides drugs and kits for treating osteoarthritis using an estrogen agonist/antagonist. The estrogen agonist/antagonist may be a compound of the formula: <see formula I> wherein A is CH2 or NR; B, D and Z are each CH or N; Y is a ring (e.g., phenyl); Z1 is a bridge; G is a (cyclic)amino; and a is 0, 1 or 2.

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