Methods for treating pain with reduced nausea and vomiting

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61P 1/08 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2667482

Methods and compositions are described for the modulation of central nervous system and/or fetal effects of substances. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of drugs and other compounds out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide for reduced nausea and vomiting in patients.

L'invention concerne des procédés et des compositions qui permettent la modulation du système nerveux central et/ou des effets fAEtaux de substances. La présente invention concerne des procédés et des compositions qui permettent la modulation de l'activité de transporteurs de refoulement pour augmenter le refoulement de médicaments et d'autres composés d'un compartiment physiologique et dans un environnement externe. En particulier, les procédés et compositions révélés ici permettent de réduire les nausées et les vomissements des patients.

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