A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/16 (2006.01) A61K 38/30 (2006.01) A61K 38/47 (2006.01) A61P 3/00 (2006.01)
Patent
CA 2669347
The present invention provides methods for treating Pompe disease in a subject by administering to the subject a therapeutically effective amount of a fusion protein which includes human acid alpha-glucosidase (GAA), or a fragment thereof, and a lysosomal targeting domain. The lysosomal targeting domain binds the human cation-independent mannose-6-phosphate receptor in a mannose-6-phosphate-independent manner.
La présente invention concerne des méthodes de traitement de la maladie de Pompe affectant un sujet, ces méthodes consistant à administrer au sujet une quantité thérapeutiquement efficace d'une protéine de fusion qui comprend une alpha-glucosidase acide humaine (GAA), ou un fragment de celle-ci, et un domaine de ciblage lysosomal. Le domaine de ciblage lysosomal lie le récepteur humain mannose-6-phosphate indépendant des cations d'une manière indépendante de mannose-6-phosphate.
Lebowitz Jonathan
Maga John
Biomarin Pharmaceutical Inc.
Fasken Martineau Dumoulin Llp
Zystor Therapeutics Inc.
LandOfFree
Methods for treating pompe disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for treating pompe disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for treating pompe disease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1643597