A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2701189
This invention relates to methods for promoting neuronal survival and regeneration using LINGO-1 antagonists and TrkB agonists. Additionally, the invention relates to methods for treating pressure induced optic neuropathies using LINGO-1 antagonists. The invention also relates generally to methods for increasing TrkB activity and inhibiting JNK pathway signaling using a LINGO-1 antagonist.
La présente invention concerne des procédés destinés à promouvoir la survie et la régénération neuronales au moyen d'antagonistes LINGO-1 et d'agonistes TrkB. En outre, l'invention concerne des procédés destinés à traiter les neuropathies optiques induites par la pression au moyen d'antagonistes LINGO-1. L'invention concerne également, d'une manière générale, des procédés destinés à accroître l'activité TrkB et à inhiber la voie de signalisation JNK au moyen d'un antagoniste LINGO-1.
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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