Methods for treating pulmonary vasoconstriction and asthma

A - Human Necessities – 61 – K

Patent

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Details

A61K 33/00 (2006.01) A61K 31/415 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61K 45/06 (2006.01) A61M 11/00 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2186892

This invention is a method for treating or preventing bronchoconstriction or reversible pulmonary vasoconstriction a mammal which method includes: a) causing the mammal to inhale a therapeutically effective amount of gaseous nitric oxide, and b) introducing into the mammal a therapeutically effective amount of phosphodiesterase inhibiting compound; and an inhaler device (10) containing nitric oxide gas, and a phosphodiesterase inhibiting compound (106).

Méthode de traitement et de prévention chez les mammifères de la bronchoconstriction ou de la vasoconstriction pulmonaire réversible consistant: (a) à leur faire inhaler une dose à effet thérapeutique d'oxyde nitrique gazeux, et (b) à leur administrer une dose à effet thérapeutique d'un composé inhibiteur de la phosphodiestérase. L'invention porte également sur un inhalateur d'oxyde nitrique gazeux et sur le composé (106) inhibiteur de la phosphodiestérase.

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