Methods for treating resistant neoplasms

A - Human Necessities – 61 – K

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A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2118096

ABSTRACT A method of treating resistant neoplasms comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula Image (I) wherein R1 and R3 are independently hydrogen, -CH3, Image , or Image , wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidino, hexamethyleneimino, and piperidino, a pharmaceutically acceptable salt or solvate thereof.

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