A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4375 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/72 (2006.01) A61K 31/473 (2006.01) A61P 15/12 (2006.01)
Patent
CA 2403791
Methods for administering apomorphine to a patient for the treatment of sexual dysfunctions while reducing undesirable side effects are disclosed. In the methods, the concentration of apomorphine is attained within the patients' plasma of up to 10 nanograms per milliliter. Advantageously, this concentration may be achieved with less than 15 % of patients so treated experiencing emesis. Methods of administration are intranasally, be inhalation to the lungs or by oral ingestion.
L'invention concerne des méthodes permettant d'administrer de l'apomorphine à un patient, pour traiter des dysfonctions sexuelles, tout en réduisant la portée d'effets secondaires indésirables. Selon ces méthodes, on parvient à une concentration en apomorphine supérieure à 10 nanogrammes par millilitre, dans le plasma des patients. Cette concentration peut être avantageusement obtenue, en ayant moins de 15 % de patients suivant ce traitement, pris de vomissements. Ces méthodes d'administration s'appliquent par voie intranasale, par inhalation dans les poumons ou par ingestion orale.
Bollinger John Daniel
Chen Yisheng
Gupta Pramod K.
Lee Dennis Y.
Reiland Thomas L.
Tap Holdings Inc.
Tap Pharmaceutical Products Inc.
Torys Llp
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