A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/48 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2284279
A method of treatment for patients with vascular occlusion and thromboembolic disorders including the acquired disease state of thrombotic stroke, by administering activated protein C. The administration of aPC provides a highly selective therapeutic agent with a low potential for causing bleeding complications. The administration of aPC is beneficial in preventing the local extension of the microvascular and macrovascular occluding arterial thrombus, thereby reducing the neurological deficit resulting from the stroke.
L'invention porte sur un procédé de traitement de patients souffrant d'occlusion vasculaire ou de troubles thromboemboliques, y compris le stade acquis consécutif à une thrombose, par administration de protéine C activée. Ladite protéine est un agent thérapeutique très sélectif à faible potentiel de complications par saignement. Son administration prévient avantageusement l'extension locale des thrombus microvasculaires et macrovasculaires, et réduit de ce fait le déficit neurologique résultant de la thrombose.
Grinnell Brian William
Howey Daniel Charles
Jackson Charles Van
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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