Methods for treating visceral pain

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4045 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2705422

The invention features methods of treating visceral pain in humans by administering an effective amount of a 5HT IB or 5HT ID receptor agonist, (e.g., a triptan). These methods can be used, for example, to treat a human suffering from visceral pain secondary to an underlying disease of a visceral organ, such as pancreatitis. Visceral pain treatable by the methods of the invention may also be secondary to a disease of the liver, kidney, ovary, uterus, bladder, bowel, stomach, esophagus, duodenum, intestine, colon, spleen, pancreas, appendix, heart, or peritoneum.

L'invention concerne des procédés de traitement de la douleur viscérale chez l'homme par l'administration d'une quantité efficace d'un agoniste des récepteurs 5HTIB ou 5HTID (c'est-à-dire un triptane). Ces procédés peuvent être utilisés par exemple pour traiter un sujet humain souffrant de douleur viscérale secondaire à une maladie sous-jacente d'un viscère telle que la pancréatite. La douleur viscérale qui peut être traitée par les procédés de l'invention peut également être secondaire à une maladie du foie, du rein, de l'ovaire, de l'utérus, de la vessie, du ventre, de l'estomac, de l'sophage, du duodénum, de l'intestin, du côlon, de la rate, du pancréas, de l'appendice, du cur ou du péritoine.

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