Methods for treatment and prevention of otitis media using...

A - Human Necessities – 61 – K

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A61K 47/30 (2006.01)

Patent

CA 2622002

Methods for treating and preventing middle ear infections by transmembrane administration of medicament-containing transmembrane carrier compositions comprising a nonionic polymer surfactant, such as an alkyl aryl polyether alcohol (e.g., tyloxapol) to the tympanic membrane. The medicaments delivered according to the methods of the invention include antibiotic, antiviral, anti- fungal and anti-inflammatory agents that are useful in treatment and/or prophylaxis of middle ear infections and their sequelae.

Procédés de traitement et de prévention des infections de l'oreille moyenne par administration transmembranaire de compositions du type vecteur transmembranaire porteuses de médicament, renfermant un tensioactif polymère non ionique, par exemple alkyle aryle polyéther alcool (comme le tyloxapol), à la membrane tympanique. On peut ainsi délivrer : antibiotiques, antiviraux, antifongiques et anti-inflammatoires utiles dans le traitement et/ou la prévention des infections de l'oreille moyenne et de leurs séquelles.

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