Methods for treatment of hiv or malaria using combinations...

Details Methods for treatment of hiv or malaria using combinations... Methods for treatment of hiv or malaria using combinations...

A - Human Necessities

61

K

A61K 31/427 (2006.01) A61K 31/4418 (2006.01) A61K 31/4433 (2006.01) A61K 31/4709 (2006.01) A61K 31/472 (2006.01) A61K 31/496 (2006.01) A61K 31/513 (2006.01) A61K 31/635 (2006.01) A61K 31/665 (2006.01) A61P 33/06 (2006.01)

Patent

CA 2676567

The present invention relates to a drug combination capable of conferring therapeutic benefits in the treatment of both AIDS and malaria. In particular, it relates to a drug combination including at least one quinolinic antimalarial compound such as chloroquine or hydroxychloroquine, and at least one inhibitor of the Human Immunodeficiency Virus (HIV) protease enzyme. This drug combination is capable of inhibiting the replication of both HIV and Plasmodium sp. It also relates to the direct antimalarial effects of the HIV PIs.

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