Methods for treatment of thiol-containing compound deficient...

A - Human Necessities – 61 – K

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A61K 38/02 (2006.01) A61K 31/12 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/711 (2006.01)

Patent

CA 2741094

Embodiments herein provide for methods for therapy of infectious diseases. In certain embodiments, methods and compositions comprise one or more agents capable of increasing thiocyanate efflux. Other embodiments further include treating an infection in a subject with an agent capable of increasing thiocyanate or thiocyanate-like compound efflux from cells of a subject thereby treating an infection in the subject. In certain embodiments, therapeutic methods involve the administration of such agents to a subject having or suspected of developing a bacterial, viral, fungal or protozoan infection.

Les modes de réalisation de la présente invention proposent des procédés thérapeutiques pour des maladies infectieuses. Dans certains modes de réalisation, les procédés et les compositions comprennent un ou plusieurs agents capables de faire augmenter l'écoulement de thiocyanate. D'autres modes de réalisation comprennent en outre le traitement d'une infection chez un sujet avec un agent capable de faire augmenter l'écoulement de thiocyanate ou de composés de type thiocyanate de cellules d'un sujet, traitant ainsi une infection chez le sujet. Dans certains modes de réalisation, des procédés thérapeutiques impliquent l'administration de ces agents à un sujet souffrant d'une ou dont on soupçonne qu'il développe une infection bactérienne, virale, fongique ou protozoaire.

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