Methods for using interferon gamma to absorb fluid from the...

A - Human Necessities – 61 – K

Patent

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A61K 38/21 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2734185

Particular aspects of the invention provide methods for decreasing the amount of fluid present in the subretinal space of the eye by administering interferon gamma to the basolateral side of the retinal pigment epithelium. Adverse ocular conditions associated with the accumulation of fluid in the subretinal space can be treated by administering an amount of interferon gamma to the basolateral side of the retinal pigment epithelium effective to remove excess fluid from the subretinal space.

L'invention concerne, selon des aspects particuliers, des procédés pour diminuer la quantité de fluide présente dans l'espace sous-rétinien de l'il, en administrant des interférons gamma au côté basolatéral de l'épithélium de pigment de rétine. Des états oculaires adverses associés à l'accumulation de fluide dans l'espace sous-rétinien peuvent être traités en administrant au côté basolatéral de l'épithélium de pigment rétinien une quantité d'interférons gamma efficace pour supprimer du fluide en excès depuis l'espace sous-rétinien.

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