Methods for using spirocyclic oxytocin antagonists

A - Human Necessities – 61 – K

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A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2037357

36/CMC5 18084 TITLE OF THE INVENTION METHODS FOR USING SPIROCYCLIC OXYTOCIN ANTAGONISTS ABSTRACT OF THE INVENTION Disclosed are spirocyclic compounds of the formula: Image (I) The compounds of formula I are oxytocin antagonists useful in the treatment of preterm labor and dysmenorrhea, and for the stoppage of labor preporatory to Caesarian delivery. Also disclosed are pharmaceutical compositions containing these compounds as well as methods for preparing the compounds.

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