Methods for using vasopressin antagonists with anthracycline...

Details Methods for using vasopressin antagonists with anthracycline... Methods for using vasopressin antagonists with anthracycline...

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/5377 (2006.01) A61K 31/5517 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2685186

The present invention relates to methods of reducing cardiotoxicity and/or improving survival from treatment with anthracycline agents comprising administering a therapeutically effective amount of a composition comprising a vasopressin antag-onist compound or a pharmaceutically acceptable salt thereof as an active ingredient, administered simultaneously or prior to the anthracycline administration.

L'invention concerne des méthodes permettant de réduire la cardiotoxicité et/ou d'améliorer la survie grâce à un traitement au moyen d'agents à base d'anthracycline. Ces méthodes consistent à administrer une quantité thérapeutiquement efficace d'une composition contenant un composé antagoniste de vasopressine ou un sel pharmaceutiquement acceptable de celui-ci comme principe actif, simultanément à l'administration d'anthracycline ou avant celle-ci.

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