Methods for vaccinating against malaria

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/015 (2006.01) A01N 43/04 (2006.01) A61K 39/005 (2006.01) A61K 39/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2502268

The invention pertains to methods for protecting against malaria infection by vaccination. The method of the invention involves priming an anti-malaria immune response with a DNA-based vaccine and boosting that response with a protein-based vaccine. The method of the invention also relates to broadening the resulting immune response by boosting with a protein-based vaccine.

L'invention se rapporte à des méthodes de protection contre le paludisme par vaccination. La méthode de l'invention consiste à déclencher une réponse immunitaire anti-paludisme au moyen d'un vaccin à base d'ADN et à amplifier cette réponse au moyen d'un vaccin à base de protéines. La méthode de l'invention se rapporte également à l'élargissement de la réponse immunitaire résultante par amplification au moyen d'un vaccin à base de protéines.

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