Methods involving induced dimerisation by cellular components

Details Methods involving induced dimerisation by cellular components Methods involving induced dimerisation by cellular components

G - Physics

01

N

G01N 33/68 (2006.01) A61K 38/48 (2006.01) A61K 49/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/532 (2006.01) G01N 33/542 (2006.01)

Patent

CA 2399934

We describe a method of inducing a cell to generate a detectable signal. The method comprises the steps of providing a cell comprising an entity and providing a first reporter and a second reporter, in which a stable interaction of the first reporter with the second reporter leads to generation of a detectable signal. The first reporter and the second reporter are allowed to bind to the entity, such that binding of the reporters to the entity leads to stable interaction of the first reporter with the second reporter and generation of a signal. The signal is preferably the activation of a cell killing mechanism.

L'invention concerne un procédé d'induction d'une cellule en vue de générer un signal détectable. Le procédé consiste à fournir une cellule comprenant une entité et à prévoir un premier reporteur et un second reporteur où une interaction stable du premier avec le second reporteur entraîne la génération d'un signal détectable. Le premier reporteur et le second reporteur sont amenés à se lier à l'entité, de telle façon que cette liaison des reporteurs à l'entité conduise à une interaction du premier reporteur avec le second reporteur et à la génération d'un signal. Le signal est de préférence l'activation d'un mécanisme de destruction d'une cellule.

Affiliated with

Also associated with

Rating

Methods involving induced dimerisation by cellular components does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods involving induced dimerisation by cellular components, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods involving induced dimerisation by cellular components will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2026107