A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/47 (2006.01) A61K 9/107 (2006.01) A61K 31/35 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/4745 (2006.01) A61K 31/565 (2006.01) A61K 33/00 (2006.01) A61K 33/10 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2300892
Methods of administering camptothecin compounds such as irinotecan hydrochloride to reduce a diarrhea side effect and methods of treating cancer and AIDs with camptothecin compounds including administering the camptothecin compounds while maintaining the intestinal lumen and the bile at an alkaline pH.
La présente invention concerne des procédés permettant l'administration de composés camptothéciniques tels que l'hydrochlorure d'irinotécane de façon à réduire la diarrhée qui lui est habituellement associée. L'invention concerne également des traitements anticancéreux et anti-SIDA à base de composés camptothéciniques. Ces traitements prévoient l'administration de tels composés camptothéciniques tout en maintenant à un pH alcalin l'intestin et la bile.
Bouscarel Bernard
Kobayashi Kunihiko
Smart & Biggar
The George Washington University
LandOfFree
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