Methods of administering crf antagonists

Details Methods of administering crf antagonists Methods of administering crf antagonists

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/33 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2151674

Substituted pyrrazoles of the formula Image I wherein R1, R2, R3, X, Y, Z and A are as defined herein with reference to formula I; pyrazoles and pyzazolopyrimidines of the formula Image V I I wherein R1, R2, R3, R4 and A are defined herein with reference to formula VII; compounds of the formula Image V I I I wherein A, R3, R4 and R5 are as defined herein with reference to formula VIII; and pyrrolopyzimidines of the formula Image IX wherein B1 R3, R4, R5 and R6 are as defined herein, with referance to formula IX, have corticotropin- releasing factor antagonist activity and as such are of use in the treatment of a variety of stress-related disorders.

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