Methods of applying ionization radiation for therapy of hiv...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 39/42 (2006.01)

Patent

CA 2606022

This invention provides methods for treating subjects infected with human immunodeficiency virus (HIV) which comprise administering to the subjects a radiolabeled antibody or agent effective to kill HIV infected cells, where the antibody or agent is specific for a HIV envelope glycoprotein. The invention also provides compositions and methods for making compositions of radiolabeled antibodies or agents to HIV envelope glycoproteins for treatment of HIV infection.

L'invention porte sur des procédés de traitement de sujets infectés par le virus d'immunodéficience (VIH), consistant à administrer à des sujets un anticorps ou un agent radiomarqué capable de tuer des cellules infectées au VIH, cet anticorps ou cet agent étant propre à la glycoprotéine d'enveloppe du VIH. Cette invention se rapporte aussi à des compositions et des procédés de fabrication de compositions d'anticorps ou d'agents radiomarqués pour des glycoprotéines d'enveloppe du VIH en vue du traitement de l'infection au VIH.

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