Methods of controlling cell differentiation and growth using...

Details Methods of controlling cell differentiation and growth using... Methods of controlling cell differentiation and growth using...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A01K 67/027 (2006.01) C07K 14/505 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2318571

This invention involves methods and materials for conferring a direct proliferative advantage on a genetically modified subpopulation of cells. Selection is then accomplished by exerting a positive selective stimulus on the engineered cells rather than a negative pressure on nonengineered cells.

Cette invention a trait à des techniques et aux substances correspondantes visant à conférer un avantage en matière de prolifération directe à une sous-population de cellules modifiées par génie génétique. On procède alors à une sélection en soumettant les cellules produites à un stimulus positif sélectif plutôt qu'en exerçant une pression négative sur des cellules non produites.

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