C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/34 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01) C40B 50/06 (2006.01) C07H 21/00 (2006.01)
Patent
CA 2548451
Subject matter includes design, synthesis, and propagation of synthetic and semi-synthetic reference nucleic acids and mixtures of reference nucleic acids for use in genetic tests, such as molecular screening, mutation testing, carrier testing, and diagnostic assays. In one implementation, methods are described for design, synthesis, and propagation of reference nucleic acid mixtures and a system is presented for using the mixtures.
La présente invention concerne la conception, la synthèse et la propagation d'acides nucléiques de référence synthétiques et semi-synthétiques, et des mélanges d'acides nucléiques de référence pour des tests de génétiques, et notamment le criblage moléculaire, le test de mutation, le test de vectorisation, et les essais de diagnostic. Dans un mode de réalisation, l'invention concerne, d'une part des procédés de conception, de synthèse et de propagation de mélanges d'acides nucléiques de référence, et d'autre part un système d'utilisation de ces mélanges.
Bejjani Bassem A.
Christensen Todd M.
Sacred Heart Medical Center
Smart & Biggar
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