Methods of determining human egg competency

Details Methods of determining human egg competency Methods of determining human egg competency

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 5/04 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2585784

The inventors have discovered inter alia, that when the chromosome complement of a first polar body (PB-I) is normal, it alone is in more than 80% of cases sufficient to predict that an embryo which has developed from an oocyte associated with the PB-I is also normal and competent. As such, the invention relates to methods of identifying competent oocytes and embryos suitable for use during in vitro fertilization.

Avec cette invention, on a découvert, entre autres choses, que lorsque la garniture chromosomique d'un premier corps polaire (PB-I) est normal, ce fait suffit à lui seul à prédire dans plus de 80 % des cas qu'un embryon qui s'est développé à partir d'un ovocyte associé à PB-I est lui aussi normal et compétent. L'invention en tant que telle concerne des procédés d'identification d'ovocytes et d'embryons susceptibles d'être utilisés dans la fécondation in vitro.

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