Methods of diagnosing and counteracting adolescent...

Details Methods of diagnosing and counteracting adolescent... Methods of diagnosing and counteracting adolescent...

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/527 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2373854

A method of diagnosing adolescent idiopathic scoliosis in a patient by determining the presence or absence of at least one mutation in melatonin signaling pathway and/or of at least one impairment in melatonin signaling in cells. A method of counteracting adolescent idiopathic scoliosis phenotype related to at least one melatonin signaling impairment in a cell by modulating melatonin signaling in the cell.

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