Methods of diagnosing and treating complications of pregnancy

Details Methods of diagnosing and treating complications of pregnancy Methods of diagnosing and treating complications of pregnancy

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/4439 (2006.01) A61K 31/455 (2006.01) A61K 31/513 (2006.01) A61K 31/522 (2006.01) A61K 38/18 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2581336

Disclosed herein are methods for diagnosing a pregnancy related hypertensive disorder or a propensity to develop a pregnancy related hypertensive disorder by measuring the level or biological activity of soluble endoglin. Also disclosed herein are methods for treating a a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using compounds that alter soluble endoglin levels or biological activity.

L'invention porte sur des méthodes de diagnostic d'un trouble de l'hypertension lié à la grossesse ou d'une propension à développer un trouble de l'hypertension lié à la grossesse, méthode consistant à mesurer le taux ou l'activité biologique de l'endogline soluble. L'invention porte également sur des méthodes de traitement d'un trouble de l'hypertension lié à la grossesse tel qu'une pré-éclampsie et une éclampsie, en utilisant des composés qui modifient les taux de l'endogline soluble ou son activité biologique.

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