Methods of diagnosing and treating pre-eclampsia or eclampsia

Details Methods of diagnosing and treating pre-eclampsia or eclampsia Methods of diagnosing and treating pre-eclampsia or eclampsia

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/4422 (2006.01) A61K 31/465 (2006.01) A61K 31/506 (2006.01) A61K 31/522 (2006.01) A61K 31/7076 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61P 9/12 (2006.01) C07K 16/28 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2496253

Disclosed herein are methods for diagnosing pre-eclampsia and eclampsia. Also disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PIGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding of VEGF or PIGF to SFltl - are also disclosed herein for the treatment of pre-eclampsia or eclampsia.

L'invention concerne des procédés de diagnostic de pré-éclampsie et d'éclampsie. Elle concerne aussi des procédés de traitement de pré-éclampsie et d'éclampsie au moyen de composés qui augmentent les niveaux de VGEF ou PIGF ou de composés qui diminuent les niveaux de sFlt-1. L'invention concerne aussi des composés qui inhibent la liaison de VEGF ou PIGF à SFltl en vue du traitement de pré-éclampsie ou d'éclampsie.

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