Methods of diagnosing inflammatory bowel disease

G - Physics – 01 – N

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G01N 33/53 (2006.01) C12N 5/16 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2632972

The present invention provides methods, systems, and code for accurately classifying whether a sample from an individual is associated with inflammatory bowel disease (IBD) or a clinical subtype thereof. In particular, the present invention is useful for classifying a sample from an individual as an IBD sample using a statistical algorithm and/or empirical data. The present invention is also useful for differentiating between a clinical subtype of IBD such as Crohn's disease (CD) and ulcerative colitis (UC) using a statistical algorithm and/or empirical data. Thus, the present invention provides an accurate diagnostic prediction of IBD or a clinical subtype thereof and prognostic information useful for guiding treatment decisions.

La présente invention a trait à des procédés, des systèmes, et un code pour la classification précise indiquant si un échantillon prélevé d'un sujet est associé à la maladie intestinale inflammatoire ou un sous-type clinique de celle-ci. En particulier, la présente invention est utile pour la classification d'un échantillon prélevé d'un sujet tel qu'un échantillon de la maladie intestinale inflammatoire à l'aide d'un algorithme statistique et/ou d'une donnée empirique. La présente invention est également utile pour la différenciation entre un sous-type clinique de la maladie intestinale inflammatoire tel que la maladie de Crohn et la rectocolite hémorragique à l'aide d'un algorithme statistique et/ou d'une donnée empirique. Ainsi, la présente invention fournit une prédiction diagnostique précise de la maladie intestinale inflammatoire ou d'un sous-type clinique de celle-ci et une information diagnostique utile pour guider les décisions de traitement.

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