Methods of diagnosing osteoarthritis

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C40B 30/00 (2006.01) G01N 33/50 (2006.01) C07K 14/52 (2006.01) C07K 14/705 (2006.01) C07K 14/78 (2006.01) C12N 15/12 (2006.01) C12N 15/19 (2006.01)

Patent

CA 2604985

A method of diagnosing osteoarthritis in a mammal is provided comprising the steps of obtaining a biological sample from the mammal; and quantifying in the sample the expression of at least one chondrocyte-specific gene or gene product, wherein a differential in expression of said gene or gene product in comparison with expression of said gene or gene product in a non--osteoarthritic mammal is indicative of osteoarthritis.

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