Methods of diagnosing & treating diabetes and insulin...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07H 21/02 (2006.01) C07K 1/00 (2006.01) C12N 5/00 (2006.01) C12N 5/08 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2487943

The present invention provides compositions and methods for diagnosing and treating diabetes and insulin resistance. In particular, the invention provides methods of identifying modulators of the polynucleotides or polypeptides of the invention and using those modulators to treat diabetes, as well as methods of diagnosing diabetes by measuring the levels of the polynucleotides or polypeptides of the invention in a patient.

La présente invention concerne des compositions et des procédés orientés vers le diagnostic et le traitement du diabète et de la résistance insulinique. L'invention concerne plus particulièrement des procédés par lesquels, d'une part on identifie des modulateurs de polynucléotides ou de polypeptides de l'invention, et d'autre part on utilise ces modulateurs pour traiter le diabète. L'invention concerne enfin des procédés permettant un diagnostic du diabète par une mesure des niveaux de polynucléotides ou de polypeptides de l'invention chez le patient considéré.

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